7-Ethyl-10-Hydroxycamptothecin
7-Ethyl-10-Hydroxycampothecin (SN-38) is a derivative from 10-hydroxycamptothecin(10-HCPT),10-HCPT is natural campthecin, a cytotoxic quinoline alkaloid originated from camtotheca acuminata or Nothapodytes pittosporoides(Mappia). This SN-38 is natural from natural camptothecin.
| Product | 7-Ethyl-10-Hydroxycamptothecin |
| Other Name | SN-38, Irinotecan related compound B |
| CAS#: | 86639-52-3 |
| Molecular Formula | C22H20N2O5 |
| Molecular Weight | 392 |
| Appearance | Yellow-white crystalline powder |
Maoyuan Series:
1. 7-Ethyl-10-Hydroxycamptothecin with purity 99% by HPLC,in house standard.
Maoyuan Advantage & Support
1. Single impurity of 7-ethyl-10-hydroxycamptothecin: less than 0.5% generally, <0.1% as required.
2.Leading natural plant ingredients supplier in China with 16 years’ experience.
3.13000 square meters production area and more than yield of 50kg 7-Ethyl-10-Hydroxycamptothecin per month.
3.ISO9001&ISO14001 certified and steady supply
4.Professional R&D team and strong R&D strength.
Packing & Storage
Packing with IATA required carton with 5kg/carton, or as customer required.
Stored in a cool, dry and dark place, shelf life 24 months.
Function:
7-Ethyl-10-Hydroxycamptothecin showed remarkable anticancer activity in preliminary clinical trials by inhibiting the DNA enzyme topoisomerase I (topo I).
Application:
1. 7-Ethyl-10-Hydroxycamptothecin is the natural starting material of Irinotecan HCl.
2. This compound 7-Ethyl-10-hydroxycamptothecin is a featured product for Apoptosis research.
Natural origins of camptothecin
1. Camptotheca acuminata (Camptotheca, Happy tree), a tree native to Hunan ,Guangxi, Sichuan province of China. Camptotheca acuminata used as a cancer treatment in Traditional Chinese Medicine.Generally, the leaves and the fruits of happy tree are applied for the extraction of camptothecin.
2. Nothapodytes pittosporoides(Mappia), a tree wild spread in Hunan ,Guangxi, Sichuan province of China. The root of the tree is applied for the extraction of campothecin, most of this origin is applied for R&D.
